Four people used rocks to break into the Woolworths at Collingwood Park about 4.15am yesterday.
The offenders, who wore tracksuits and had their heads covered, gained access to cash tills inside the store, but no money was kept at the premises and they left empty handed.
The Criminal Investigation Branch is investigating the break-in, along with two others which were committed at Woolworths supermarkets at Fernvale and Karalee in the early hours of Wednesday morning.
They said a red Ford sedan had been used in each of the offences.
Police said a group of youths wearing masks smashed a glass window at the Fernvale supermarket, obtaining an undisclosed sum of cash and cigarettes before fleeing in the red Ford.
No more than half an hour later, the same group of tracksuit-wearing crooks was thought to have driven the red sedan to Junction Rd, Karalee, where they were disturbed by witnesses after breaking into another supermarket.
They fled without stealing property.
Police have also linked the group to the burglary of a bottle shop in the Brisbane suburb of Mansfield, which occurred about 2.30am Wednesday.
Investigations into each of the break and enter offences is continuing.
Police are yet to provide detailed descriptions of the offenders or the vehicle they were seen driving.
As of yesterday, there was no CCTV footage available from the latest break-in.
Anyone with information that could assist police should contact Crime Stoppers on 1800 333 000.